Thermo Fisher Scientific ABCE1 Polyclonal Antibody

Thermo Fisher Scientific ABCE1 Polyclonal Antibody

Applications

• Western Blot (WB): 1:500–1:2,000

Species Reactivity

• Human
• Mouse

Host / Isotype

• Rabbit / IgG

Class

• Polyclonal

Type

• Antibody

Immunogen

Fusion protein corresponding to a region derived from internal residues of human ATP-binding cassette, sub-family E (OABP), member 1.

Conjugate

• Unconjugated

Form

• Liquid

Concentration

• 1.1 mg/mL

Purification

• Antigen affinity chromatography

Storage Buffer

• PBS, pH 7.4, with 40% glycerol

Contains

• 0.05% sodium azide

Storage Conditions

• −20°C

Shipping Conditions

• Wet ice

RRID

• AB_2635740

Product Specific Information

The antibody detects endogenous levels of total ABCE1 protein.

Target Information

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White).
This protein is a member of the OABP subfamily and is also known as the RNase L inhibitor. It functions to block the activity of ribonuclease L, which, when activated, inhibits protein synthesis in the 2-5A/RNase L system—the central pathway for viral interferon action. Two transcript variants encoding the same protein have been identified for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.