Thermo Fisher Scientific ABCE1 Polyclonal Antibody

Thermo Fisher Scientific ABCE1 Polyclonal Antibody

Applications

• Western Blot (WB): 1:500–1:2,000

Species Reactivity

• Human
• Mouse

Host / Isotype

• Rabbit / IgG

Class

• Polyclonal

Type

• Antibody

Immunogen

Fusion protein corresponding to a region derived from internal residues of human ATP-binding cassette, sub-family E (OABP), member 1.

Conjugate

• Unconjugated

Form

• Liquid

Concentration

• 1.1 mg/mL

Purification

• Antigen affinity chromatography

Storage Buffer

• PBS, pH 7.4, with 40% glycerol

Contains

• 0.05% sodium azide

Storage Conditions

• −20°C

Shipping Conditions

• Wet ice

RRID

• AB_2635740

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Product Specific Information

The antibody detects endogenous levels of total ABCE1 protein.

Target Information

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White).
This protein is a member of the OABP subfamily and is also known as the RNase L inhibitor. It functions to block the activity of ribonuclease L, which, when activated, inhibits protein synthesis in the 2-5A/RNase L system—the central pathway for viral interferon action. Two transcript variants encoding the same protein have been identified for this gene.

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For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.