Thermo Fisher Scientific alpha Adducin Polyclonal Antibody
Thermo Fisher Scientific의 alpha Adducin 폴리클로날 항체는 인간 단백질을 인식하며 Western blot, IHC, ICC/IF, IP 등 다양한 응용에 적합합니다. Rabbit IgG 기반으로 항원 친화 크로마토그래피로 정제되었으며, 연구용으로만 사용 가능합니다.
- 카탈로그번호
- PA5117767
- 판매단위
- pk
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:1,000–1:5,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| Immunoprecipitation (IP) | 1–5 µL/mg of lysate |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | E. coli-derived Human ADD1/adducin 1 fragment |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Antigen affinity chromatography, Protein A |
| Storage Buffer | PBS, pH 7 |
| Contains | 0.03% ProClin 300 |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2902378 |
Target Information
Adducins are a family of cytoskeletal proteins encoded by three genes (alpha, beta, gamma). Adducin is a heterodimeric protein consisting of related subunits produced from distinct genes but sharing a similar structure.
Alpha- and beta-adducin include a protease-resistant N-terminal region and a protease-sensitive, hydrophilic C-terminal region. Alpha- and gamma-adducins are ubiquitously expressed, while beta-adducin is highly expressed in brain and hematopoietic tissues.
Adducin binds with high affinity to Ca(2+)/calmodulin and serves as a substrate for protein kinases A and C. Alternative splicing results in multiple variants encoding distinct isoforms, though not all have been fully characterized.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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