Thermo Fisher Scientific PDE4B Polyclonal Antibody, Biotin
PDE4B 단백질을 인식하는 Biotin-conjugated rabbit polyclonal 항체. Western blot, IHC, ICC, ELISA, IP 등 다양한 응용에 적합. Human, Mouse, Rat 반응성. Affinity chromatography로 정제된 고품질 항체. -20°C에서 보관.
- 카탈로그번호
- PD4B-212-BIOTIN
- 판매단위
- pk
카탈로그
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (IHC) | 1:50–1:250 |
| Immunocytochemistry (ICC/IF) | 1:50–1:250 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
| Immunomicroscopy (IM) | 1:50–1:200 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide common to all PDE4B subtypes taken near C-terminal |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer, pH 7.4–7.8, with 0.5% BSA, 30% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The PDE4B gene belongs to the type IV, cyclic AMP (cAMP)-specific, cyclic nucleotide phosphodiesterase (PDE) family. Cyclic nucleotides are key second messengers regulating various cellular responses to extracellular signals such as hormones, light, and neurotransmitters. PDEs modulate intracellular cyclic nucleotide levels, playing a crucial role in signal transduction. This gene encodes a protein that hydrolyzes cAMP specifically, and its altered activity has been linked to schizophrenia and bipolar affective disorder. Multiple splice variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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