Thermo Fisher Scientific PTMA Polyclonal Antibody
Human PTMA 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC(P) 및 ICC/IF에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, PBS(glycerol 포함) 용액 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:20–1:50 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human PTMA. Recombinant protein control fragment (Product #RP-99547). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2646115 |
Product Specific Information
Immunogen sequence:
EVVEEAENGR DAPANGNANE ENGEQEADNE VDEEEE
Antigen sequence identity:
Mouse - 97%, Rat - 97%
Target Information
The thymus gland produces several hormones or hormone-like substances derived from a polypeptide precursor known as prothymosin-alpha (113 amino acids in rat). Thymosin-alpha-1, a 28-amino-acid peptide, was originally isolated from calf thymosin fraction 5 and shown to restore immune function in several test systems. It was later found to have the same sequence in human and bovine thymosin-alpha-1.
In 2003, Jiang et al. identified a pathway regulating mitochondria-initiated caspase activity, in which PHAP promoted caspase-9 activation after apoptosome formation, while prothymosin-alpha-1 negatively regulated caspase-9 activation by inhibiting apoptosome formation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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