Thermo Fisher Scientific TMEM106B Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthesized peptide derived from human TMEM106B(Accession Q9NUM4), corresponding to amino acid residues V45-K95. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:TMEM106B,uniProtId:Q9NUM4-1,ncbiNodeId:9606,antigenRange:45-95,antigenLength:274,antigenImageFileName:PA5-100353_TMEM106B_Q9NUM4-1_Rabbit.svg,antigenImageFileNamePDP:PA5-100353_TMEM106B_Q9NUM4-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice

RRID

AB_2849866

Product Specific Information

Antibody detects endogenous levels of total TMEM106B.

Target Information

Transmembrane protein 106B (TMEM106B) is a single-pass transmembrane protein that is thought to be a novel risk factor for frontotemporal lobar degeneration (FTLD), a group of clinically, pathologically and genetically heterogeneous disorders associated with atrophy in the frontal lobe and temporal lobe of the brain. The actual role of TMEM106B, and that of the closely related protein TMEM106A are still undetermined.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.