Thermo Fisher Scientific RNF34 Polyclonal Antibody
Human RNF34 단백질을 인식하는 Rabbit Polyclonal 항체로 Western blot에 적합합니다. 합성 펩타이드 면역원으로 제작되었으며, 비결합(Unconjugated) 상태로 제공됩니다. 고순도의 Affinity chromatography 정제 방식으로 생산되어 높은 특이성과 재현성을 제공합니다.
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- PA5113677
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Applications and Tested Dilution
- Western Blot (WB): 0.2–1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the middle region of human RNF34 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2884192 |
Product Specific Information
- Immunogen sequence: LVDLVLCHHG LGSEDDMDTS SLNSSRSQTS SFFTRSFFSN YTAPSATMSS
- Storage guidance:
- Short term: 2–8°C (up to 1 week)
- Long term: -20°C in small aliquots to prevent freeze-thaw cycles
- Predicted homology:
Cow: 87%; Dog: 93%; Guinea Pig: 80%; Horse: 93%; Human: 100%; Rabbit: 80%; Rat: 93%
Target Information
The protein encoded by the RNF34 gene contains a RINF finger domain, a motif involved in protein–protein and protein–DNA interactions. It interacts with DNAJA3/hTid-1, a DnaJ protein known to modulate apoptosis. Overexpression in HeLa cells confers resistance to TNF-alpha–induced apoptosis, indicating an anti-apoptotic role. RNF34 can be cleaved by caspase-3 during apoptosis, and alternatively spliced transcript variants encoding distinct isoforms have been reported.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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