Thermo Fisher Scientific SUR1 Polyclonal Antibody
Thermo Fisher Scientific의 SUR1 Polyclonal Antibody는 인간, 마우스, 랫트에서 반응하며 Western blot, IHC, ELISA에 적합합니다. KLH 결합 합성 펩타이드(aa 301-400)를 면역원으로 사용한 Rabbit IgG 폴리클로날 항체로, 단백질 A로 정제되고 1 mg/mL 농도의 액상 형태입니다. 연구용으로만 사용 가능합니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human SUR1, amino acids 301–400 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The protein encoded by this gene is a member of the ATP-binding cassette (ABC) transporter superfamily. ABC proteins transport various molecules across extra- and intra-cellular membranes and are divided into seven distinct subfamilies. This protein belongs to the MRP subfamily, involved in multi-drug resistance. It modulates ATP-sensitive potassium channels and insulin release. Mutations in this protein are linked to hyperinsulinemic hypoglycemia of infancy and non-insulin-dependent diabetes mellitus type II. Alternative splicing has been observed, though transcript variants are not fully described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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