Thermo Fisher Scientific NUSAP1 Polyclonal Antibody
Thermo Fisher Scientific NUSAP1 Polyclonal Antibody는 인간, 생쥐, 랫트 시료에 반응하는 Rabbit IgG 기반 항체입니다. IHC, ICC, ELISA 등 다양한 응용에 적합하며, 고순도 Protein A 정제 및 안정적인 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human NUSAP1, amino acids 151–250 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Ubiquitin exists either covalently attached to another protein or free (unanchored). When covalently bound, it conjugates to target proteins via an isopeptide bond as monoubiquitin or polyubiquitin chains linked through different Lys residues or via the initiator Met. Polyubiquitin chains have distinct functions depending on linkage type:
- Lys-6: DNA repair
- Lys-11: ERAD and cell-cycle regulation
- Lys-29: Lysosomal degradation
- Lys-33: Kinase modification
- Lys-48: Proteasomal degradation
- Lys-63: Endocytosis, DNA-damage responses, NF-κB activation
Linear polymer chains (Met-linked) are involved in cell signaling.
Free polyubiquitin also plays roles in kinase activation and signaling.
60S ribosomal protein L40 is a component of the 60S ribosomal subunit, essential for translation of specific transcripts, particularly for cap-dependent translation of vesicular stomatitis virus mRNAs.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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