Thermo Fisher Scientific TCL1A Monoclonal Antibody (1 21)
TCL1A 단백질을 타깃하는 Mouse IgG2b monoclonal antibody로, WB, IHC, ICC, ELISA, IP 등 다양한 응용에 사용 가능. 인간 TCL1A 발현 연구에 적합하며 AKT 경로 분석에 유용. 액상 형태로 −20°C 보관.
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Thermo Fisher Scientific TCL1A Monoclonal Antibody (1 21)
Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 2 µg/mL | View 1 publication |
| Immunohistochemistry (IHC) | Assay-dependent | View 1 publication |
| Immunocytochemistry (ICC/IF) | 5 µg/mL | - |
| ELISA | Assay-dependent | - |
| Immunoprecipitation (IP) | Assay-dependent | - |
Product Specifications
| Specification | Description |
|---|---|
| Published Species | Human |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1 21 |
| Immunogen | Recombinant full-length human TCL-1A protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Storage Conditions | −20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2533415 |
Target Information
Overexpression of the TCL1 gene in humans has been implicated in the development of mature T-cell leukemia, in which chromosomal rearrangements bring the TCL1 gene in close proximity to the T-cell antigen receptor (TCR)-alpha or TCR-beta regulatory elements (Virgilio et al., 1998).
In normal T cells, TCL1 is expressed in CD4-/CD8- cells but not in cells at later stages of differentiation.
TCL1 functions as a coactivator of the cell survival kinase AKT (Laine et al., 2000).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지 파일명: 39-4800_TCL1A_TCL1_P56279-1_House_mouse.svg, 39-4800_TCL1A_TCL1_P56279-1_House_mouse_PDP.jpeg)
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