Thermo Fisher Scientific TCL1A Monoclonal Antibody (1 21)
TCL1A 단백질을 타깃하는 Mouse IgG2b monoclonal antibody로, WB, IHC, ICC, ELISA, IP 등 다양한 응용에 사용 가능. 인간 TCL1A 발현 연구에 적합하며 AKT 경로 분석에 유용. 액상 형태로 −20°C 보관.
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Thermo Fisher Scientific TCL1A Monoclonal Antibody (1 21)
Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 2 µg/mL | View 1 publication |
| Immunohistochemistry (IHC) | Assay-dependent | View 1 publication |
| Immunocytochemistry (ICC/IF) | 5 µg/mL | - |
| ELISA | Assay-dependent | - |
| Immunoprecipitation (IP) | Assay-dependent | - |
Product Specifications
| Specification | Description |
|---|---|
| Published Species | Human |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1 21 |
| Immunogen | Recombinant full-length human TCL-1A protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Storage Conditions | −20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2533415 |
Target Information
Overexpression of the TCL1 gene in humans has been implicated in the development of mature T-cell leukemia, in which chromosomal rearrangements bring the TCL1 gene in close proximity to the T-cell antigen receptor (TCR)-alpha or TCR-beta regulatory elements (Virgilio et al., 1998).
In normal T cells, TCL1 is expressed in CD4-/CD8- cells but not in cells at later stages of differentiation.
TCL1 functions as a coactivator of the cell survival kinase AKT (Laine et al., 2000).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일명: 39-4800_TCL1A_TCL1_P56279-1_House_mouse.svg, 39-4800_TCL1A_TCL1_P56279-1_House_mouse_PDP.jpeg)
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