Thermo Fisher Scientific Human THRA, Ligand Binding Domain, GST Tag Recombinant Protein

Applications

Tested Dilution

Publications

Ligand Binding Assay (LBA)

Assay-dependent

-

Product Specifications

Species

Human

Expression System

Baculovirus

Amino acid sequence

148-410

Tag

GST-tag

Class

Recombinant

Type

Protein

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

See Label

Purification

purified

Storage buffer

proprietary buffer

Contains

no preservative

Storage conditions

-80° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Dry ice

Product Specific Information

Thyroid Receptor alpha, Ligand Binding Domain (THRA LBD ) is a 57.90 kDa recombinant human protein (amino acids 148-410) expressed as a GST-tagged fusion protein in baculovirus-infected insect cells. THRA LBD was expressed and purified in the absence of exogenous ligands, making it ideal for ligand binding and coregulator displacement studies.

Protein Form: Recombinant, Ligand Binding Domain

Target Information

The protein encoded by this gene is a nuclear hormone receptor for triiodothyronine. It is one of the several receptors for thyroid hormone, and has been shown to mediate the biological activities of thyroid hormone. Knockout studies in mice suggest that the different receptors, while having certain extent of redundancy, may mediate different functions of thyroid hormone. Alternatively spliced transcript variants encoding distinct isoforms have been reported.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.