Thermo Fisher Scientific ASCC1 Polyclonal Antibody

Applications and Tested Dilutions

Product Specifications

Product Specific Information

• Immunogen sequence:
  MEVLRPQLIR IDGRNYRKNP VQEQTYQHEE DEEDFYQGSM ECADEPCDAY EVEQTPQGFR STLRAPSLLY KHIVGKRGDT RKKIEMETKT SISIPKPGQD GEIVITGQHR NGVISARTRI DVLLDTFRRK QPFTHFLAFF LNEVEVQEGF LRFQEEVLAK CSMDHGVDSS IFQNPKKLHL
• Positive Samples: Rat pancreas
• Cellular Location: Cytoplasm

Target Information

This gene encodes a subunit of the activating signal cointegrator 1 (ASC-1) complex, a transcriptional coactivator involved in gene transactivation by multiple transcription factors such as AP-1, NF-κB, and SRF.
The encoded protein contains an N-terminal KH-type RNA-binding motif required for AP-1 transactivation by the ASC-1 complex.
Mutations in this gene are associated with Barrett esophagus and esophageal adenocarcinoma.
Alternatively spliced transcripts encoding multiple isoforms have been observed.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.