Thermo Fisher Scientific CHOP Recombinant Rabbit Monoclonal Antibody (6G2E1)
CHOP 단백질 검출용 Thermo Fisher Scientific의 재조합 토끼 단클론 항체. Western blot, IHC, ELISA 등에 적합하며 높은 특이성과 재현성을 제공. HEK293 세포에서 발현된 IgG 형 항체로, 안정적인 액상 형태로 공급.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:2,000 |
| ELISA | 1 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 6G2E1 |
| Immunogen | Synthetic peptide within amino acids 1–100 of human DDIT3/CHOP (NP_004074.2) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 0.05% BSA, 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_3094267 |
Product Specific Information
Immunogen sequence:
MAAESLPFSF GTLSSWELEA WYEDLQEVLS SDENGGTYVS PPGNEEEESK IFTTLDPASL AWLTEEEPEP AEVTSTSQSP HSPDSSQSSL AQEEEEEDQG
Target Information
GADD153 (also known as CHOP) is a small nuclear protein capable of dimerizing with transcription factors C/EBP alpha and beta. This dimerization inhibits normal C/EBP binding and function, while conferring binding activity to non-classical stress-related targets. Under normal conditions, GADD153 is not expressed at detectable levels but is highly upregulated under cellular or ER stress, such as tunicamycin treatment, nutrient starvation, or reducing agents affecting calcium flux across the ER membrane.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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