Thermo Fisher Scientific Phospho-RSK2 (Tyr529) Polyclonal Antibody
RSK2 단백질의 Tyr529 인산화 형태를 특이적으로 인식하는 Rabbit Polyclonal 항체. Western blot 및 IHC(Paraffin)에 사용 가능. 인간, 마우스, 랫트 반응성. PBS/glycerol buffer에 보관되며 -20°C에서 안정적. 연구용 전용 제품.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human RPS6KA3 (Accession P51812), corresponding to amino acid residues around phosphorylated Tyr529. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2903284 |
Product Specific Information
This antibody detects endogenous levels of RSK2 only when phosphorylated at Tyr529.
Target Information
RPS6KA3 (RSK2) is a serine/threonine kinase that modulates many cellular processes including transcription, adhesion, growth, survival, and proliferation. It contains two non-identical kinase catalytic domains and phosphorylates various substrates, including members of the MAPK signaling pathway. The activity of this protein is implicated in controlling cell growth and differentiation. Mutations in the gene are associated with Coffin-Lowry syndrome (CLS).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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