Thermo Fisher Scientific SPZ1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

2.5 µg/mL

-

Product Specifications

Species Reactivity

Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

synthetic peptide directed towards the C terminal region of mouse SPZ1 if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:SPZ1,uniProtId:Q99MY0-1,ncbiNodeId:10090,antigenRange:378,antigenLength:378,antigenImageFileName:PA5-68871_SPZ1_Q99MY0-1_Rabbit.svg,antigenImageFileNamePDP:PA5-68871_SPZ1_Q99MY0-1_Rabbit_PDP.jpeg,sortOrder:2}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

PBS with 2% sucrose

Contains

0.09% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2692284

Product Specific Information

This target displays homology in the following species: Mouse: 100%

Target Information

Spermatogenic leucine zipper protein 1 is a member of the basic helix-loop-helix (bHLH) family of transcription factors which is expressed specifically in the testis and epididymis. Studies show that SPZ1 acts downstream of mitogen-activated protein kinase (MAPK), an extracellular signal-regulated kinase 1/2 to up-regulate cell proliferation and tumorigenesis. Also, through an interaction with proliferating cell nuclear antigen (PCNA) promoter, SPZ1 induced cell proliferation concomitant with an increase in PCNA gene expression.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.