Thermo Fisher Scientific Human RXRB, Ligand Binding Domain, GST Tag Recombinant Protein

Applications

• Ligand Binding Assay (LBA)

Tested Dilution: Assay-dependent

Product Specifications

Product Specific Information

Retinoid X receptor beta, ligand binding domain (RXRB-LBD) is a 54.5 kDa recombinant human protein (amino acids 295–533) expressed as a GST-tagged fusion protein in insect cells. RXRB-LBD is expressed and purified in the absence of exogenous ligands, making it ideal for ligand binding and coregulator recruitment studies.
Protein Form: Recombinant, Ligand Binding Domain

Target Information

This gene encodes a member of the retinoid X receptor (RXR) family of nuclear receptors which are involved in mediating the effects of retinoic acid (RA). This receptor forms homodimers with the retinoic acid, thyroid hormone, and vitamin D receptors, increasing both DNA binding and transcriptional function on their respective response elements. The gene lies within the major histocompatibility complex (MHC) class II region on chromosome 6.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.