Thermo Fisher Scientific Phospho-Cannabinoid Receptor 2 (Thr338, Thr340) Polyclonal Antibody
인산화된 Cannabinoid Receptor 2(Thr338, Thr340)를 특이적으로 인식하는 Rabbit Polyclonal 항체. Western blot에 최적화되어 있으며, 항원 친화 크로마토그래피로 정제됨. 인간 시료 반응성, 액상 형태, 4°C 보관 권장.
- 카탈로그번호
- 7TM0057B
- 판매단위
- pk
카탈로그
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Applications
- Western Blot (WB): 1:1,000 dilution
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic phosphopeptide derived from human CB2 around the phosphorylation site of Thr338/Thr340 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Dulbecco’s PBS, pH 7.4 |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice (domestic); Dry ice (international) |
Target Information
Cannabinoids exert their well-known physiological effects through two G protein-coupled receptors, cannabinoid receptor 1 (CB1) and CB2. Both receptors inhibit adenylyl cyclase and stimulate the mitogen-activated protein kinase (MAPK) pathway. CB1 receptors also modulate ion channels through direct G-protein interactions. Delta 9-tetrahydrocannabinol and related ligands likely exert their psychoactive effects by inhibiting presynaptic N- and P/Q-type calcium channels. CB2 is thought to function primarily in the immune system, though it may also be present in the central nervous system, including the retina.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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