Thermo Fisher Scientific PD L1 (CD274) Monoclonal Antibody (OTI4G4)
Human PD-L1(CD274) 단백질을 인식하는 Mouse IgG1 단클론 항체. Western blot과 Flow cytometry에 사용 가능. Lyophilized 형태로 제공되며 PBS+8% trehalose buffer에 보관. 종양 면역 회피 연구에 적합.
- 카탈로그번호
- CF812995
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific PD L1 (CD274) Monoclonal Antibody (OTI4G4)
Applications
Western Blot (WB)
- Tested Dilution: 1:500
Flow Cytometry (Flow)
- Tested Dilution: 1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4G4 |
| Immunogen | Full length human recombinant protein of human CD274 (NP_054862) produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, we recommend adding 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
To use this carrier-free antibody for conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
Programmed death receptor ligand 1 (PD-L1, also known as B7-H1) is a member of the B7 family. It binds to the programmed death receptor 1 (PD-1), which negatively regulates T-cell receptor (TCR) signaling. PD-L1 engagement reduces TCR-mediated proliferation and cytokine production. PD-L1 is abundantly expressed in many murine and human cancers and can be upregulated by IFN-gamma stimulation, suggesting its role in tumor immune evasion.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.