Thermo Fisher Scientific SEC24B Polyclonal Antibody

Applications

Western Blot (WB)

• Assay-dependent

Immunoprecipitation (IP)

• 2–10 µg/mg lysate

Product Specifications

Product Specific Information

• Recommended shelf life: 1 year from date of receipt.

Target Information

Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER).
The COPII coat has two main functions:

1. Physical deformation of the ER membrane into vesicles.
2. Selection of cargo molecules for transport to the Golgi complex.

SEC24B plays a central role in cargo selection within the COPII complex. Together with SEC24A, it may have different specificity compared to SEC24C and SEC24D.
It may preferentially package cargos with cytoplasmic DxE or LxxLE motifs and can also recognize conformational epitopes.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.