Thermo Fisher Scientific EYA4 Polyclonal Antibody

Applications

Immunohistochemistry (IHC)

• Tested Dilution: 1:100–1:500

Immunohistochemistry (Paraffin) (IHC (P))

• Tested Dilution: 1:100–1:500

Product Specifications

Product Specific Information

• Recommended shelf life: 1 year from date of receipt
• Based on 100% sequence identity, this antibody is predicted to react with Rat, X. tropicalis, Bovine, Dog, Rabbit, Guinea pig, Pig, Panda, Orangutan, Monkey, Gorilla, Chimpanzee, and Naked mole rat.

Target Information

This gene encodes a member of the eyes absent (EYA) family of proteins. The encoded protein may act as a transcriptional activator through its protein phosphatase activity and may be important for eye development and for continued function of the mature organ of Corti.
Mutations in this gene are associated with postlingual, progressive, autosomal dominant hearing loss (deafness, autosomal dominant non-syndromic sensorineural 10 locus).
The encoded protein is also a putative oncogene that mediates DNA repair, apoptosis, and innate immunity following DNA damage, cellular damage, and viral attack.
Defects in this gene are also associated with dilated cardiomyopathy 1J.
Alternative splicing results in multiple transcript variants encoding distinct isoforms.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

제품 이미지

(이미지 파일명: IHC-00728_EYA4_O95677-1_Rabbit.svg, IHC-00728_EYA4_O95677-1_Rabbit_PDP.jpeg)