Thermo Fisher Scientific BMP-2 Monoclonal Antibody (7D10G8E2)
BMP-2 단백질을 인식하는 Mouse IgG2b 단일클론 항체로 ELISA에 적합합니다. 인간, 마우스, 개, 원숭이, 랫트 등 다양한 종에 반응합니다. Protein A로 정제된 액상 형태이며, -20°C에서 보관합니다. 연구용으로만 사용 가능합니다.
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- MA541060
- 판매단위
- pk
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Applications
ELISA
- Tested Dilution: 1:5,000–1:10,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Dog, Human, Mouse, Rhesus monkey, Rat |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 7D10G8E2 |
| Immunogen | Recombinant Human BMP-2 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Dry ice (international) |
| RRID | AB_2898814 |
Target Information
Bone Morphogenic Proteins (BMPs) are members of the TGF-beta superfamily involved in bone and cartilage formation (Hogan 1996, Reddi 1998, Francis-West et al. 1999). Mature BMPs are 30–38 kDa proteins with a TGF-beta-like cysteine knot configuration. Lovostatin increases bone formation by activating the bmp-2 gene (Mundy et al. 1999). BMPs stimulate the production of bone matrix proteins and influence stromal cell and osteoclast proliferation (Macias et al. 1999, Lecanda et al. 1997). They also play roles in visceral development, cell proliferation, apoptosis, differentiation, and morphogenesis (Hogan 1996, Dale and Wardle 1999). BMPs are key regulators of dorsal/ventral patterning and signal through type II and type I receptors to activate the Smad pathway (Massague 1994, Derynck 1997, Attisano 1993).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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