Thermo Fisher Scientific GORAB Monoclonal Antibody (OTI2H6), TrueMAB
Human GORAB 단백질(aa 35-394)에 특이적인 마우스 단클론 항체로 Western blot에 적합합니다. TrueMAB 포맷으로 높은 특이성과 재현성을 제공하며, 액상 형태로 1 mg/mL 농도로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications
- Western Blot (WB)
Tested Dilution
- 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2H6 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 35–394 of human GORAB produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
TCEB1, also known as protein elongin C, is a subunit of the transcription factor B (SIII) complex composed of elongins A/A2, B, and C. This complex activates elongation by RNA polymerase II by suppressing transient pausing within transcription units.
Elongin A functions as the transcriptionally active component, while elongins B and C serve as regulatory subunits. Elongin A2 is expressed specifically in the testis and forms a stable complex with elongins B and C.
The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, thereby inhibiting transcription elongation.
Western blot tests using two different antibodies against unique regions of this protein confirm consistent molecular weight results.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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