Thermo Fisher Scientific COL5A1 Monoclonal Antibody (2F4)

Applications

Tested Dilution

Publications

Western Blot (WB)

1-5 µg/mL

-

ELISA (ELISA)

3 ng/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG1, kappa

Class

Monoclonal

Type

Antibody

Clone

2F4

Immunogen

COL5A1 (AAH08760, 1 a.a. approximately 591 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:COL5A1,uniProtId:P20908-1,ncbiNodeId:9606,antigenRange:1-1838,antigenLength:1838,antigenImageFileName:H00001289-M01_COL5A1_P20908-1_House_mouse.svg,antigenImageFileNamePDP:H00001289-M01_COL5A1_P20908-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

See Label

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Sequence of this protein is as follows: MGPPGPPGPR GPSGAPGADG PQGPPGGIGN PGAVGEKGEP GEAGEPGLPG EGGPPGPKGE RGEKGESGPS GAAGPPGPKG PPGDDGPKGS PGPVGFPGDP GPPGEPGPAG QDGPPGDKGD DGEPGQTGSP GPTGEPGPSG PPGKRGPPGP AGPEGRQGEK GAKGEAGLEG PPGKTGPIGP QGAPGKPGPD GLRGIPGPVG EQGLPGSPGP DGPPGPMGPP GLPGLKGDSG PKGEKGHPGL IGLIGPPGEQ GEKGDRGLPG PQGSSGPKGE QGITGPSGPI GPPGPPGLPG PPGPKGAKGS SGPTGPKGEA GHPGPPGPPG PPGEVIQPLP IQASRTRRNI DASQLLDDGN GENYVDYADG MEEIFGSLNS LKLEIEQMKR PLGTQQNPAR TCKDLQLCHP DFPDGEYWVD PNQGCSRDSF KVYCNFTAGG STCVFPDKKS EGARITSWPK ENPGSWFSEF KRGKLLSYVD AEGNPVGVVQ MTFLRLLSAS AHQNVTYHCY QSVAWQDAAT GSYDKALRFL GSNDEEMSYD NNPYIRALVD GCATKKGYQK TVLEIDTPKV EQVPIVDIMF NDFGEASQKF GFEVGPACFM G

Target Information

Type I collagen, the fibrillar collagen found in most connective tissues, and the only component of the collagen found in cartilage. Mutations in this gene are associated with osteogenesis imperfecta, Ehlers-Danlos syndrome, and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for platelet-derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.