
Thermo Fisher Scientific Sex Hormone Binding Globulin (SHBG) Monoclonal Antibody (SPM605)
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Applications
Tested Dilution
Publications
Immunohistochemistry (Paraffin) (IHC (P))
Assay-dependent
Immunohistochemistry (PFA fixed) (IHC (PFA))
1-2 µg/mL
Immunocytochemistry (ICC/IF)
1-2 µg/mL
Flow Cytometry (Flow)
1-2 µg/10^6 cells
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse / IgG1, kappa
Class
Monoclonal
Type
Antibody
Clone
SPM605
Immunogen
Recombinant full-length human SHBG protein if (typeof window.$mangular === undefined
|| !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{
targetFamily:
SHBG,
uniProtId:
P04278-1,
ncbiNodeId:
9606,
antigenRange:
1-402,
antigenLength:
402,
antigenImageFileName:
6462-MSM1X-P0_SHBG_P04278-1_House_mouse.svg,
antigenImageFileNamePDP:
6462-MSM1X-P0_SHBG_P04278-1_House_mouse_PDP.jpeg,
sortOrder:
1}\]
; $mangular.isB2BCMGT = false
; $mangular.isEpitopesModalImageMultiSizeEnabled = true
;
View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}
Conjugate
Unconjugated Unconjugated Unconjugated
Form
Liquid
Concentration
200 µg/mL
Purification
Protein A/G
Storage buffer
PBS, pH 7.4, with 0.05% BSA
Contains
0.05% sodium azide
Storage conditions
4° C, do not freeze
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
SHBG is a steroid binding protein that was first described as a plasma protein secreted by the liver and is thought to participate in the regulation of steroid responses. SHBG transports androgens and estrogens in the blood, binding each steroid molecule as a dimer formed from identical or nearly identical monomers. Low plasma SHBG levels are associated with obesity, abdominal adiposity, metabolic syndrome, and predict the development of type 2 diabetes. Polymorphisms in this gene have been associated with polycystic ovary syndrome and type 2 diabetes mellitus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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