Thermo Fisher Scientific IFITM2 Monoclonal Antibody (OTI4E3), TrueMAB
인간 IFITM2 단백질을 인식하는 Mouse IgG2a 단클론 항체. Western Blot 및 Immunohistochemistry에 최적화. 항바이러스 연구용으로 적합하며, 고순도 액상 형태로 제공. -20°C 보관, 반복 동결/해동 회피 권장.
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- TA811626
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Applications
Western Blot (WB)
- Tested Dilution: 1:500
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4E3 |
| Immunogen | Full length human recombinant protein of human IFITM2 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Target Information
IFN-induced antiviral protein which inhibits the entry of viruses to the host cell cytoplasm, permitting endocytosis but preventing subsequent viral fusion and release of viral contents into the cytosol.
Active against multiple viruses, including influenza A virus, SARS-CoV, Marburg virus (MARV), Ebola virus (EBOV), Dengue virus (DNV), West Nile virus (WNV), HIV-1, and vesicular stomatitis virus (VSV).
Can inhibit viral entry mediated by influenza virus hemagglutinin, MARV and EBOV GP1,2, SARS-CoV S protein, and VSV G protein.
Induces cell cycle arrest and mediates apoptosis by caspase activation in a p53-independent manner.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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