Thermo Fisher Scientific BRD2 Polyclonal Antibody
BRD2 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, 인간 시료에 반응합니다. ICC/IF에 사용 가능하며, 고순도의 Affinity chromatography로 정제되었습니다. PBS 기반 버퍼에 40% 글리세롤 포함, 장기 보관 시 -20°C에서 안정적입니다.
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence (range: 555–602). Recombinant protein control fragment: Product # RP-109932 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_3091910 |
Product Specific Information
- Immunogen sequence:
KKKRKAEKHR GRAGADEDDK GPRAPRPPQP KKSKKASGSG GGSAALGP - Antigen sequence identity:
Mouse 77%; Rat 75%
Target Information
This gene encodes a transcriptional regulator belonging to the BET (bromodomains and extra terminal domain) family of proteins. It associates with transcription complexes and acetylated chromatin during mitosis and selectively binds to the acetylated lysine-12 residue of histone H4 via its two bromodomains. The gene maps to the MHC class II region on chromosome 6p21.3, but sequence comparison suggests that the protein is not involved in the immune response. This gene has been implicated in juvenile myoclonic epilepsy, a common form of epilepsy that becomes apparent in adolescence. Multiple alternatively spliced variants have been described, though the full-length nature of some variants has not been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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