Thermo Fisher Scientific MAP2K3 Monoclonal Antibody (OTI3D10), TrueMAB
MAP2K3 단백질을 인식하는 Mouse monoclonal antibody로 Western blot에 최적화됨. Human, Mouse, Dog 반응성. Lyophilized 형태로 제공되며, 고순도 Affinity chromatography로 정제. 연구용으로 세포 신호전달 및 MAPK 경로 분석에 적합.
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- CF505642
- 판매단위
- pk
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Applications
- Western Blot (WB): 1:200–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Dog, Human, Mouse |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3D10 |
| Immunogen | Full length human recombinant protein of human MAP2K3 produced in HEK293T cells (Target Family: MEK3, UniProt ID: P46734-1, Antigen Range: 1–347) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (recommended: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
MAP2K3 (MEK3) is a dual-specificity protein kinase involved in cellular signal transduction pathways. It phosphorylates and activates MAPK14/p38-MAPK and plays a role in glucose transporter expression. Activation occurs via insulin signaling and RAS oncogene expression, contributing to oncogenic transformation. Inhibition of MAP2K3 is associated with the pathogenesis of Yersinia pseudotuberculosis. Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported.
For Research Use Only.
Not for use in diagnostic procedures or resale without authorization.
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