Thermo Fisher Scientific CD11c Monoclonal Antibody (3.9), PE-eFluor 610, eBioscience
인간 CD11c 단백질을 인식하는 단클론 항체로, PE-eFluor 610 형광 표지되어 유세포분석(Flow Cytometry)에 최적화됨. 다양한 면역세포 표면 분석에 사용 가능하며, 4°C 암소 보관 필요. 연구용 한정 제품.
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Applications and Tested Dilution
- Application: Flow Cytometry (Flow)
- Tested Dilution: 5 µL (0.5 µg)/test
- Publications: View 17 publications
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human, Rhesus monkey |
| Host / Isotype | Mouse / IgG1, kappa |
| Recommended Isotype Control | Mouse IgG1 kappa Isotype Control (P3.6.2.8.1), PE-eFluor™ 610, eBioscience™ |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 3.9 |
| Conjugate | PE-eFluor™ 610 |
| Excitation/Emission Max | 565/606 nm |
| Form | Liquid |
| Concentration | 5 µL/Test |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 0.2% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2574532 |
Available Formats
- Unconjugated
- Alexa Fluor 532
- Alexa Fluor 700
- APC
- APC-eFluor 780
- Biotin
- Brilliant UV 737
- Brilliant UV 805
- eFluor 450
- eFluor 506
- FITC
- PE
- PE-Cyanine5
- PE-Cyanine5.5
- PE-Cyanine7
- PerCP-eFluor 710
- Super Bright 600
- Super Bright 645
- Super Bright 702
- Super Bright 780
- Request custom conjugation
Product Specific Information
The 3.9 monoclonal antibody reacts with human CD11c, a 150 kDa integrin alpha X chain. CD11c associates with beta2 integrin to form the CD11c/CD18 heterodimer, expressed on monocytes, granulocytes, macrophages, NK cells, dendritic cells, and subsets of T and B lymphocytes. This complex binds to CD54, iC3b, and fibrinogen, playing a key role in leukocyte adhesion.
- Applications Reported: Flow cytometric analysis
- Applications Tested: Pre-titrated for flow cytometry using normal human peripheral blood cells
- Use 5 µL (0.5 µg) per test (100 µL final volume)
- Suitable for 10⁵–10⁸ cells/test
Fluorophore Information:
PE-eFluor® 610 is excited by 488–561 nm lasers and emits at 607 nm. Recommended detection filter: 610/20 band pass (PE-Texas Red® equivalent).
Light Sensitivity:
Protect from light to prevent photo-induced oxidation.
Fixation:
Samples can be stored up to 3 days at 4°C in the dark using:
Excitation: 488–561 nm
Emission: 607 nm
Laser Compatibility: Blue, Green, Yellow-Green lasers
Filtration: 0.2 µm post-manufacturing filtered
Target Information
CD11, together with CD18, forms a heterodimer adhesion molecule.
- CD11a: Expressed on B/T lymphocytes, macrophages, monocytes, neutrophils, basophils, eosinophils
- CD11b: Expressed by monocytes, macrophages, NK cells, some B/T cells, granulocytes
- CD11c: Expressed on monocytes, macrophages, NK cells, some granulocytes, and a subset of lymphocytes
For Research Use Only. Not for use in diagnostic procedures or resale without authorization.
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