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Thermo Fisher Scientific CD11c Monoclonal Antibody (3.9), PE-eFluor 610, eBioscience
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Thermo Fisher Scientific CD11c Monoclonal Antibody (3.9), PE-eFluor 610, eBioscience

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인간 CD11c 단백질을 인식하는 단클론 항체로, PE-eFluor 610 형광 표지되어 유세포분석(Flow Cytometry)에 최적화됨. 다양한 면역세포 표면 분석에 사용 가능하며, 4°C 암소 보관 필요. 연구용 한정 제품.

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Thermo Fisher Scientific 61-0116-42 CD11c Monoclonal Antibody (3.9), PE-eFluor 610, eBioscience 100 tests pk판매 단위 pk
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Thermo Fisher Scientific · Thermo Fisher Scientific CD11c Monoclonal Antibody (3.9), PE-eFluor 610, eBioscience

Applications and Tested Dilution

  • Application: Flow Cytometry (Flow)
  • Tested Dilution: 5 µL (0.5 µg)/test
  • Publications: View 17 publications

Product Specifications

항목 내용
Species Reactivity Human
Published Species Human, Rhesus monkey
Host / Isotype Mouse / IgG1, kappa
Recommended Isotype Control Mouse IgG1 kappa Isotype Control (P3.6.2.8.1), PE-eFluor™ 610, eBioscience™
Class Monoclonal
Type Antibody
Clone 3.9
Conjugate PE-eFluor™ 610
Excitation/Emission Max 565/606 nm
Form Liquid
Concentration 5 µL/Test
Purification Affinity chromatography
Storage Buffer PBS, pH 7.2, with 0.2% BSA
Contains 0.09% sodium azide
Storage Conditions 4°C, store in dark, DO NOT FREEZE
Shipping Conditions Ambient (domestic); Wet ice (international)
RRID AB_2574532

Available Formats

  • Unconjugated
  • Alexa Fluor 532
  • Alexa Fluor 700
  • APC
  • APC-eFluor 780
  • Biotin
  • Brilliant UV 737
  • Brilliant UV 805
  • eFluor 450
  • eFluor 506
  • FITC
  • PE
  • PE-Cyanine5
  • PE-Cyanine5.5
  • PE-Cyanine7
  • PerCP-eFluor 710
  • Super Bright 600
  • Super Bright 645
  • Super Bright 702
  • Super Bright 780
  • Request custom conjugation

Product Specific Information

The 3.9 monoclonal antibody reacts with human CD11c, a 150 kDa integrin alpha X chain. CD11c associates with beta2 integrin to form the CD11c/CD18 heterodimer, expressed on monocytes, granulocytes, macrophages, NK cells, dendritic cells, and subsets of T and B lymphocytes. This complex binds to CD54, iC3b, and fibrinogen, playing a key role in leukocyte adhesion.

  • Applications Reported: Flow cytometric analysis
  • Applications Tested: Pre-titrated for flow cytometry using normal human peripheral blood cells
    • Use 5 µL (0.5 µg) per test (100 µL final volume)
    • Suitable for 10⁵–10⁸ cells/test

Fluorophore Information:
PE-eFluor® 610 is excited by 488–561 nm lasers and emits at 607 nm. Recommended detection filter: 610/20 band pass (PE-Texas Red® equivalent).

Light Sensitivity:
Protect from light to prevent photo-induced oxidation.

Fixation:
Samples can be stored up to 3 days at 4°C in the dark using:

Excitation: 488–561 nm
Emission: 607 nm
Laser Compatibility: Blue, Green, Yellow-Green lasers
Filtration: 0.2 µm post-manufacturing filtered


Target Information

CD11, together with CD18, forms a heterodimer adhesion molecule.

  • CD11a: Expressed on B/T lymphocytes, macrophages, monocytes, neutrophils, basophils, eosinophils
  • CD11b: Expressed by monocytes, macrophages, NK cells, some B/T cells, granulocytes
  • CD11c: Expressed on monocytes, macrophages, NK cells, some granulocytes, and a subset of lymphocytes

For Research Use Only. Not for use in diagnostic procedures or resale without authorization.


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