Thermo Fisher Scientific BTBD12 Polyclonal Antibody, MaxPab
BTBD12 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, 인간 시료에 반응하며 Western blot에 적합합니다. 액상 형태로 제공되며 PBS 버퍼에 보관됩니다. DNA 복구 관련 연구용으로 사용됩니다.
- 카탈로그번호
- H00084464-B01P
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific BTBD12 Polyclonal Antibody, MaxPab
Thermo Fisher Scientific BTBD12 Polyclonal Antibody, MaxPab
Applications
- Western Blot (WB)
Tested Dilution: 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | BTBD12 (AAH36335.1, 1–1151 a.a) full-length human protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
MVNNPHLSDV QFQTDSGEVL YAHKFVLYAR CPLLIQYVNN EGFSAVEDGV LTQRVLLGDV STEAARTFLH YLYTADTGLP PGLSSELSSL AHRFGVSELV HLCEQVPIAT DSEGKPWEEK EAENCESRAE NFQELLRSMW ADEEEEAETL LKSKDHEEDQ ENVNEAEMEE IYEFAATQRK LLQEERAAGA GEDADWLEGG SPVSGQLLAG VQVQKQWDKV EEMEPLEPGR DEAATTWEKM GQCALPPPQG QHSGARGAEA PEQEAPEEAL GHSSCSSPSR DCQAERKEGS LPHSDDAGDY EQLFSSTQGE ISEPSQITSE PEEQSGAVRE RGLEVSHRLA PWQASPPHPC RFLLGPPQGG SPRGSHHTSG SSLSTPRSRG GTSQVGSPTL LSPAVPSKQK RDRSILTLSK EPGHQKGKER RSVLECRNKG VLMFPEKSLS IDLTQSNPDH SSSRSQKSSS KLNEEDEVIL LLDSDEELEL EQTKMKSISS DPLEEKKALE ISPRSCELFS IIDVDADQEP SQSPPRSEAV LQQEDEGALP ENRGSLGRRG APWLFCDRES SPSEASTTDT SWLVPATPLA SRSRDCSSQT QISSLRSGLA VQAVTQHTPR ASVGNREGNE VAQKFSVIRP QTPPPQTPSS CLTPVSPGTS DGRRQGHRSP SRPHPGGHPH SSPLAPHPIS GDRAHFSRRF LKHSPPGPSF LNQTPAGEVV EVGDSDDEQE VASHQANRSP PLDSDPPIPI DDCCWHMEPL SPIPIDHWNL ERTGPLSTSS PSRRMNEAAD SRDCRSPGLL DTTPIRGSCT TQRKLQEKSS GAGSLGNSRP SFLNSALWDV WDGEEQRPPE TPPPAQMPSA GGAQKPEGLE TPKGANRKKN LPPKVPITPM PQYSIMETPV LKKELDRFGV RPLPKRQMVL KLKEIFQYTH QTLDSDSEDE SQSSQPLLQA PHCQTLASQT YKPSRAGVHA QQEATTGPGA HRPKGPAKTK GPRHQRKHHE SITPPSRSPT KEAPPGLNDD AQIPASQESV ATSVDGSDSS LSSQSSSSCE FGAAFESAGE EEGEGEVSAS QAAVQAADTD EALRCYIRSK PALYQKVLLY QPFELRELQA ELRQNGLRVS SRRLLDFLDT HCITFTTAAT RREKLQGRRR QPRGKKKVER N
Target Information
This gene encodes a structure-specific endonuclease subunit. The encoded protein contains a central BTB domain and forms a multiprotein complex with ERCC4(XPF)-ERCC1, MUS81-EME1, and SLX1 endonucleases. It also associates with MSH2/MSH3 mismatch repair complex, telomere binding complex TERF2(TRF2)-TERF2IP(RAP1), protein kinase PLK1, and C20orf94.
This multiprotein complex is essential for repair of specific DNA lesions and critical for cellular responses to replication fork failure. The encoded protein acts as a docking platform for assembly of multiple structure-specific endonucleases.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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