Thermo Fisher Scientific FGFR5 Polyclonal Antibody
FGFR5 단백질을 인식하는 Rabbit Polyclonal 항체로, Human, Mouse, Rat 시료에 반응합니다. WB, IHC, ICC, ELISA 등 다양한 응용에 사용 가능하며, Protein A로 정제된 1 mg/mL 농도의 액상 제품입니다. -20°C에서 보관합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | Assay-dependent |
| Immunohistochemistry (Paraffin) (IHC-P) | Assay-dependent |
| Immunohistochemistry (Frozen) (IHC-F) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide derived from human FGFR5/FGFRL1 (amino acids 231–330) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Acidic and basic fibroblast growth factors (FGFs) are members of a family of multifunctional polypeptide growth factors that stimulate proliferation of cells of mesenchymal, epithelial, and neuro-ectodermal origin. FGFs act by binding and activating specific cell surface receptors. Six members of the FGF receptor family have been identified and cloned: FGFR-1 (Flg), FGFR-2 (BEK), FGFR-3, FGFR-4, FGFR-5, and FGFR-6. These receptors typically contain an extracellular ligand-binding region with three immunoglobulin-like domains, a transmembrane domain, and a cytoplasmic tyrosine kinase domain. However, FGFR-5 lacks the cytoplasmic kinase domain. FGFR-5 is expressed in various tissues including kidney, brain, and lung, with preferential expression in the pancreas, where it may play a role in regulating pancreatic function.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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