Thermo Fisher Scientific LILRA4 Polyclonal Antibody
Thermo Fisher Scientific의 LILRA4 Polyclonal Antibody는 인간 LILRA4 단백질(aa 240–450)에 특이적으로 반응하는 rabbit IgG 항체입니다. Western blot과 ELISA에 적합하며, 액상 형태로 제공됩니다. 연구용으로 Type I IFN 조절 연구에 활용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:2,000 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing amino acids 240–450 of human LILRA4 (NP_036408.4) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.56 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2855324 |
Product Specific Information
Immunogen sequence:
LTLQCGSDVG YIRYTLYKEG ADGLPQRPGR QPQAGLSQAN FTLSPVSRSY GGQYRCYGAH NVSSEWSAPS DPLDILIAGQ ISDRPSLSVQ PGPTVTSGEK VTLLCQSWDP MFTFLLTKEG AAHPPLRLRS MYGAHKYQAE FPMSPVTSAH AGTYRCYGSR SSNPYLLSHP SEPLELVVSG ATETLNPAQK KSDSKTAPHL QDYTVENLIR M
Target Information
ILT7 is a pDC-specific IgG-like transcript and a member of the leukocyte immunoglobulin-like receptor gene family. This receptor, in complex with FcER1a, transduces ITAM-mediated signals that negatively modulate type I IFN production by pDC.
ILT7 is a potential target for regulating Type I IFN production by pDC, which play major roles in viral infection, autoimmune diseases, and anti-cancer immunity.
Additionally, ILT7, along with CD123 and BDCA-2, can be used to identify or classify subsets of pDC along with TLR expression and TLR-mediated immune responses.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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