Thermo Fisher Scientific SF3B2 Polyclonal Antibody
Human SF3B2 단백질을 인식하는 Rabbit Polyclonal Antibody. Western blot, IHC, ICC/IF에 사용 가능. 항원 친화 크로마토그래피로 정제. PBS 기반 용액 형태로 제공되며 4°C 또는 -20°C에서 보관. 연구용으로만 사용 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human SF3B2. Recombinant protein control fragment (Product #RP-100756). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2647179 |
Product Specific Information
Immunogen sequence:
MSTVMSRKGP APELQGVEVA LAPEELELDP MAMTQKYEEH VREQQAQVEK EDFSDMVAEH AAKQKQKKRK AQPQDSRGGS KKYKEFK
Highest antigen sequence identity to the following orthologs:
Mouse – 100%, Rat – 100%.
Target Information
Subunit of the splicing factor SF3B required for A complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence-independent binding of SF3A/SF3B complex upstream of the branch site is essential; it may anchor U2 snRNP to the pre-mRNA. May also be involved in the assembly of the E complex. Belongs also to the minor U12-dependent spliceosome, which is involved in the splicing of a rare class of nuclear pre-mRNA introns.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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