Thermo Fisher Scientific NeuN Polyclonal Antibody
NeuN 단백질을 타겟으로 하는 Rabbit Polyclonal Antibody로, 인간·마우스·랫트에서 반응성이 검증됨. Western blot, IHC, ICC 등 다양한 응용 가능. 항원 친화 크로마토그래피로 정제되어 높은 특이성과 재현성을 제공. 연구용으로만 사용.
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Thermo Fisher Scientific NeuN Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:3,000 | View 1 publication |
| Immunohistochemistry (IHC) | – | View 4 publications |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 | – |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:1,000 | – |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 | View 1 publication |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of Mouse NeuN. The exact sequence is proprietary. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.42 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 20% glycerol |
| Contains | 0.025% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2736207 |
Product Specific Information
- Positive Control: Mouse brain, Rat brain
- Predicted Reactivity: Rhesus Monkey (100%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Fox-3, also known as NeuN, HRNBP3, RBFOX3 (RNA binding protein, fox-1) or Fox-1 homolog C, is a 350 amino acid protein containing one RRM (RNA recognition motif) domain.
Localized to both the nucleus and cytoplasm, Fox-3 regulates alternative splicing events.
The Fox-3 gene is located on human chromosome 17, which encodes over 1,200 genes and includes key tumor suppressor genes p53 and BRCA1.
- p53: Maintains genetic integrity through DNA repair and apoptosis regulation.
- BRCA1: Involved in DNA repair; mutations linked to early-onset breast and ovarian cancers.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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