
Thermo Fisher Scientific L-Plastin Recombinant Rabbit Monoclonal Antibody (JE48-95)
Thermo Fisher Scientific의 L-Plastin Recombinant Rabbit Monoclonal Antibody (JE48-95)는 인간 L-Plastin을 표적으로 하는 고특이성 항체입니다. WB, IHC, Flow Cytometry에 적합하며, 높은 순도(Protein A 정제)와 안정적인 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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- MA534865
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- pk
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Flow Cytometry (Flow) | 1:50–1:100 |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | JE48-95 |
| Immunogen | Recombinant protein within Human Plastin L (aa 461–627) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 40% glycerol, 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, avoid freeze/thaw cycles, store in dark |
| Shipping Conditions | Wet ice |
| RRID | AB_2848773 |
Product Specific Information
Positive control samples include human tonsil tissue, lung cancer tissue, colon tissue, appendix tissue, and spleen tissue.
Target Information
L-plastin is a leukocyte-specific actin bundling protein from the fimbrin family. It contains two actin-binding domains and two EF-hand calcium-binding domains. Phosphorylation occurs on a serine residue in its headpiece region in response to inflammatory stimuli. L-plastin is implicated in integrin-mediated adhesion regulation in leukocytes and is expressed in many human cancer cell lines derived from solid tumors. Expression is upregulated by testosterone in androgen receptor-positive prostate and breast cancer cells through upstream androgen receptor binding elements.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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