Thermo Fisher Scientific DCTN2 Polyclonal Antibody
DCTN2 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, IHC, ICC/IF, ELISA 등 다양한 응용에 사용 가능. Human, Mouse, Rat 반응성. Protein A로 정제된 1 mg/mL 액상 제품으로 -20°C 보관.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | Assay-dependent |
| Immunohistochemistry (Frozen) (IHC-F) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide derived from human Dynamitin/DCTN2 (amino acids 65–150) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The DCTN2 gene encodes a 50-kDa subunit of dynactin, a macromolecular complex composed of 10–11 subunits ranging from 22 to 150 kDa. Dynactin binds to both microtubules and cytoplasmic dynein, participating in multiple cellular processes including ER-to-Golgi transport, lysosome and endosome movement, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit exists in 4–5 copies per dynactin molecule and contains three short α-helical coiled-coil domains that may mediate interactions with other subunits, including the largest subunit (p150).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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