Thermo Fisher Scientific CA1 Monoclonal Antibody (10E4)
CA1 단백질을 인식하는 Mouse IgG2a 형 단일클론 항체로, Western blot 및 ELISA에 적합. Human 시료 반응성 확인됨. Affinity chromatography로 정제된 액상 제품이며, 연구용으로만 사용 가능.
- 카탈로그번호
- H00000759-M19
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1–5 µg/mL
ELISA
- Tested Dilution: 0.3 ng/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 10E4 |
| Immunogen | CA1 (AAH27890, 1–261 a.a) full-length recombinant protein with GST tag (MW of GST tag alone: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
MASPDWGYDD KNGPEQWSKL YPIANGNNQS PVDIKTSETK HDTSLKPISV SYNPATAKEI INVGHSFHVN FEDNDNRSVL KGGPFSDSYR LFQFHFHWGS TNEHGSEHTV DGVKYSAELH VAHWNSAKYS SLAEAASKAD GLAVIGVLMK VGEANPKLQK VLDALQAIKT KGKRAPFTNF DPSTLLPSSL DFWTYPGSLT HPPLYESVTW IICKESISVS SEQLAQFRSL LSNVEGDNAV PMQHNNRPTQ PLKGRTVRAS F
Target Information
Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in various biological processes, including:
- Respiration
- Calcification
- Acid-base balance
- Bone resorption
- Formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid
CA1 is closely linked to CA2 and CA3 genes on chromosome 8 and encodes a cytosolic protein found at the highest level in erythrocytes. Variants of this gene have been described in some populations. Multiple alternatively spliced variants encoding the same protein have been identified. Transcript variants of CA1 utilizing alternative polyA sites have been described in literature.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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