Thermo Fisher Scientific C21ORF2 Monoclonal Antibody (1E4)
C21ORF2 단백질을 인식하는 Thermo Fisher Scientific의 단클론 항체로, ELISA 검증 완료. 인간 시료에 반응하며 IgG2a 아이소타입의 Mouse monoclonal antibody. 연구용으로 Down syndrome 관련 미토콘드리아 기능 연구에 활용 가능.
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Applications and Tested Dilution
- Application: ELISA
- Tested Dilution: 3 ng/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1E4 |
| Immunogen | C21orf2 (NP_004919, 1 a.a. ~ 101 a.a) partial recombinant protein with GST tag. MW of GST tag alone is 26 kDa. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
MKLTRKMVLT RAKASELHSV RKLNCWGSRL TDISICQEMP SLEVITLSVN SISTLEPVSR CQRLSELYLR RNRIPSLAEL FYLKGLPRLR VLWLAENPCC G
Target Information
Four alternatively spliced transcript variants encoding four different isoforms have been found for this nuclear gene.
All isoforms contain leucine-rich repeats.
Three isoforms are mitochondrial proteins, while one lacks the target peptide and is not located in mitochondrion.
This gene is down-regulated in Down syndrome (DS) brain, which may represent mitochondrial dysfunction in DS patients.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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