Thermo Fisher Scientific Myeloperoxidase/MPO Monoclonal Antibody (MPO/7116)
인간 MPO 단백질을 인식하는 마우스 모노클로날 항체로, IHC(P) 및 IHC(PFA)에서 사용 가능. 단백질 A/G로 정제된 액상 형태이며, 보존제 없이 PBS(pH 7.4)에 저장. 연구용으로만 사용 가능.
- 카탈로그번호
- 4353-MSM6-P1ABX
- 판매단위
- pk
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: Assay-dependent
Immunohistochemistry (PFA fixed) (IHC (PFA))
- Tested Dilution: 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | MPO/7116 |
| Immunogen | Recombinant fragment (around aa150–250) of human MPO protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Target Information
Myeloperoxidase (MPO) is a heme protein synthesized during myeloid differentiation and is a major component of neutrophil azurophilic granules. It is produced as a single-chain precursor and subsequently cleaved into light and heavy chains. The mature MPO forms a tetramer composed of two light and two heavy chains. This enzyme generates hypohalous acids critical for the microbicidal activity of neutrophils. Diseases associated with MPO include Myeloperoxidase Deficiency and Familial Alzheimer’s Disease type 1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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