Thermo Fisher Scientific Phospho-IFNAR1 (Ser535, Ser539) Polyclonal Antibody
Human IFNAR1 단백질의 Ser535 및 Ser539 인산화 부위를 인식하는 rabbit polyclonal antibody. Western blot에 적합하며, 1:500–1:1,000 희석 사용 권장. 액상 형태, 1 mg/mL 농도, -20°C 보관.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
- Suggested Positive Control: 293 cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide sequence around phosphorylation site of serine 535 or serine 539 (D-S(p)-G-N-Y-S(p)-N) derived from Human Interferon-α Receptor Type I Subunit I |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2554397 |
Product Specific Information
A suggested positive control for Western blot is 293 cells.
Target Information
Interferons are widely used therapeutic agents due to their antitumor and antiviral effects, as well as their modulatory effects on the immune system (Biron, 2001; Kirkwood, 2002). These cytokines exert their effects by binding to the Type I Interferon Receptor (IFNAR1). Down-regulation of this receptor plays a key role in determining the magnitude and duration of cytokine signaling, which is influenced by phosphorylation of Serine 535 and 539 in IFNAR1 (Kumar et al., 2003).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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