Thermo Fisher Scientific FGFR2 Monoclonal Antibody (1G3)
Human FGFR2 단백질을 인식하는 Mouse monoclonal antibody로 Western blot, IHC, ELISA에 적합. 고순도 affinity chromatography로 정제되었으며 PBS buffer에 보존. 세포 성장, 분화, 암 연구용으로 활용 가능.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 5 µg/mL |
| ELISA | 0.03 ng/mL |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1G3 |
| Immunogen | FGFR2 (AAH39243, 621–723 a.a) partial recombinant protein with GST tag (MW of GST tag: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
GHRMDKPANC TNELYMMMRD CWHAVPSQRP TFKQLVEDLD RILTLTTNEE YLDLSQPLEQ YSPSYPDTRS SCSSGDDSVF SPDPMPYEPC LPQYPHINGS VKT
Target Information
FGFR2 is a member of the FGFR family of receptor tyrosine kinases. This family regulates various cellular functions including angiogenesis, mitogenesis, osteogenesis, myogenesis, carcinogenesis, cellular differentiation, and tissue repair after injury.
FGFR family members differ in ligand affinities and tissue distribution. Mutations in FGFR2 are associated with several syndromes such as Crouzon, Pfeiffer, Craniosynostosis, Apert, Jackson-Weiss, Beare-Stevenson cutis gyrata, Saethre-Chotzen, and syndromic craniosynostosis.
Multiple alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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