Thermo Fisher Scientific BMP-5 Polyclonal Antibody
Rabbit polyclonal antibody against human BMP-5. Validated for WB and IHC (Paraffin). High purity (>95%) via antigen affinity chromatography. Supplied as liquid form in PBS with 50% glycerol. Suitable for research use only.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 130–180 of Human BMP-5 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2719157 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using an epitope-specific immunogen. The purity is greater than 95% as determined by SDS-PAGE.
Target Information
TGF-β family members are key modulators of cell proliferation, differentiation, matrix synthesis, and apoptosis. BMPs (Bone Morphogenetic Proteins) initiate, promote, and regulate the development, growth, and remodeling of bone and cartilage. Beyond skeletal functions, BMPs also play roles in prenatal development and postnatal growth, remodeling, and maintenance of various tissues and organs.
BMP-5 is expressed in the nervous system, lungs, and liver, and acts as a regulator of dendritic growth in sympathetic neurons. It is a 454 amino acid precursor protein cleaved to release the biologically active C-terminal mature protein.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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