Thermo Fisher Scientific WNK1 Recombinant Superclonal Antibody (3HCLC)

Applications

Immunocytochemistry (ICC/IF)

• Tested Dilution: 2 µg/mL

Product Specifications

Product Specific Information

This antibody is predicted to react with Monkey, Rabbit, Pig, and Mouse.

Recombinant rabbit Superclonal™ antibodies are unique offerings from Thermo Fisher Scientific.
They consist of multiple different recombinant monoclonal antibodies, combining the sensitivity of polyclonal antibodies with the specificity of monoclonal antibodies, and ensuring consistency through recombinant production.
These antibodies recognize multiple epitope sites, providing higher detection sensitivity for low abundance targets.
Each lot can be reproduced exactly, avoiding biological variability typical of polyclonal antibodies.

Note: Formerly called “Recombinant polyclonal antibody”, this product is now rebranded as “Recombinant Superclonal™ antibody”. The physical product and performance remain unchanged.

Target Information

WNK1 serine/threonine kinase is a member of the WNK subfamily.
WNK1 may regulate blood pressure by controlling sodium and chloride ion transport.
Mutations in this gene are associated with pseudohypoaldosteronism type II and hereditary sensory neuropathy type II.
WNK1 plays a role in electrolyte homeostasis, cell signaling, survival, and proliferation.
It acts as an activator and inhibitor of sodium- and potassium-coupled chloride cotransporters respectively.
WNK1 localizes to the distal nephron, involved in salt, potassium, and pH homeostasis.
Mutations in the WNK gene can lead to pseudohypoaldosteronism and neuropathy.

For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.

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