Thermo Fisher Scientific UPRT Monoclonal Antibody (OTI2F2), TrueMAB
Human UPRT 단백질을 인식하는 mouse monoclonal antibody로, Western blot, IHC, ICC/IF에 적합. Lyophilized 형태로 제공되며, 고순도 affinity chromatography로 정제됨. 연구용으로만 사용 가능.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:4,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2F2 |
| Immunogen | Full length human recombinant protein of human UPRT produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of about 1 mg/mL.
For conjugation experiments, perform an additional desalting step (Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
The UPRT gene encodes uracil phosphoribosyltransferase, which catalyzes the conversion of uracil and 5-phosphoribosyl-1-R-diphosphate to uridine monophosphate (UMP).
This reaction is crucial in nucleotide metabolism, specifically the pyrimidine salvage pathway.
The enzyme localizes to the nucleus and cytoplasm and is a potential target for drug design against parasitic infections and cancer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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