Thermo Fisher Scientific Cystatin A Monoclonal Antibody (CPTC-CSTA-1)
Cystatin A 단백질을 표적하는 Mouse 모노클로날 항체로 Western blot 및 IHC에 사용 가능. Human 반응성, Protein A/G 정제, 4°C 보관. 연구용으로만 사용 가능.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 2–4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2c, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | CPTC-CSTA-1 |
| Immunogen | Recombinant full-length human CSTA protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some members are active cysteine protease inhibitors, while others have lost or never acquired this inhibitory activity.
There are three inhibitory families in the superfamily: type 1 cystatins (stefins), type 2 cystatins, and kininogens.
This gene encodes a stefin that functions as a cysteine protease inhibitor, forming tight complexes with papain and cathepsins B, H, and L.
The protein is one of the precursor proteins of the cornified cell envelope in keratinocytes and plays a role in epidermal development and maintenance.
Stefins have been proposed as prognostic and diagnostic tools for cancer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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