
Thermo Fisher Scientific IL17RE Polyclonal Antibody
IL17RE 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체로, Human 및 Mouse 시료에 반응합니다. Western Blot과 ELISA에 적합하며, 세포막 및 세포질 단백질 검출에 유용합니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 24–260 of human IL17RE (NP_7056131) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.98 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2805756 |
Product Specific Information
Immunogen sequence:
AGIGFRHLPH WNTRCPLASH TDDSFTGSSA YIPCRTWWAL FSTKPWCVRV WHCSRCLCQH LLSGGSGLQR GLFHLLVQKS KKSSTFKFYR RHKMPAPAQR KLLPRRHLSE KSHHISIPSP DISHKGLRSK RTQPSDPETW ESLPRLDSQR HGGPEFSFDL LPEARAIRVT ISSGPEVSVR LCHQWALECE ELSSPYDVQK IVSGGHTVEL PYEFLLPCLC IEASYLQEDT VRRKKCP
Positive Samples: HT-29, A-549, A-431, Mouse kidney, Mouse thymus
Cellular Location: Cell membrane, Cytoplasm, Single-pass type I membrane protein
Target Information
The interleukin 17 receptor E (IL-17RE) shares limited similarity to the receptor of IL-17A, a ubiquitous type I membrane glycoprotein that, together with IL-17A, plays a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis.
IL-17RE is the functional receptor of IL-17C and has been suggested to mediate mucosal immunity to infection with intestinal pathogens. IL-17C is produced by epithelia in response to bacterial challenge and binds to a receptor complex formed by IL-17RE and IL-17RA on the epithelial cell surface, thereby regulating the immune function of epithelial cells in an autocrine manner.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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