Thermo Fisher Scientific MTOR Monoclonal Antibody (OTI1D5), TrueMAB
인간 mTOR 단백질(aa1766-2144)에 특이적인 Mouse IgG1 단일클론 항체. Western blot에 1:2000 희석으로 검증됨. 액상형, 1 mg/mL 농도, PBS/BSA/glycerol 완충액에 보관. 세포 성장 및 암 관련 신호전달 연구용.
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Applications
- Western Blot (WB): Tested dilution 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1D5 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1766–2144 of human MTOR produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
FRAP1 (mTOR) is a serine/threonine kinase that plays a critical role in cellular growth and proliferation. Perturbations in the mTOR/PI3-kinase/AKT pathway are associated with numerous forms of cancer. FRAP1 is also the target of rapamycin and its analogues, which are currently used as immunosuppressants and cancer therapeutics. Mutations affecting the gene result in Smith-Kingsmore syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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