Thermo Fisher Scientific CAS Polyclonal Antibody
인간 CSE1L 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody입니다. IHC 및 ICC/IF에 사용 가능하며, 항원 친화 크로마토그래피로 정제되었습니다. PBS 기반 용액으로 제공되며 장기 보관 시 -20°C에서 안정적입니다.
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- PA583402
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- pk
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Thermo Fisher Scientific CAS Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:20–1:50 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human CSE1L. Recombinant protein control fragment (Product #RP-102804). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Lot-Specific |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2790558 |
Product Specific Information
Immunogen sequence:
HGITQANELV NLTEFFVNHI LPDLKSANVN EFPVLKADGI KYIMIFRNQV PKEHLLVSIP LLINHLQAES IVVHTYAAHA LERLFTMRGP NNATLF
Target Information
Proteins that carry a nuclear localization signal (NLS) are transported into the nucleus by the importin-alpha/beta heterodimer. Importin-alpha binds the NLS, while importin-beta mediates translocation through the nuclear pore complex. After translocation, RanGTP binds importin-beta and displaces importin-alpha. Importin-alpha must then be returned to the cytoplasm, leaving the NLS protein behind. The encoded protein binds strongly to NLS-free importin-alpha, and this binding is released in the cytoplasm by RANBP1 and RANGAP1. It may also play roles in apoptosis and cell proliferation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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