Thermo Fisher Scientific ME3 Polyclonal Antibody
Thermo Fisher Scientific의 ME3 Polyclonal Antibody는 인간, 마우스, 랫트 시료에 반응하며 WB, IHC, ICC, ELISA 등에 사용 가능합니다. Rabbit IgG 폴리클로날 항체로, 정제된 액상 형태이며 PBS/glycerol buffer에 보관됩니다. 연구용으로만 사용됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 505–604 of human ME3 (NP_001014811.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.64 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2913968 |
Product Specific Information
Positive test controls include:
- HT-29
- 293T
- Mouse brain, heart, kidney
- Rat brain, heart, kidney
Subcellular location: Mitochondrion matrix
Immunogen sequence:
IRHIPDEIFL LTAEQIAQEV SEQHLSQGRL YPPLSTIRDV SLRIAIKVLD YAYKHNLASY YPEPKDKEAF VRSLVYTPDY DSFTLDSYTW PKEAMNVQTV
Target Information
ME3 proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis, metastasis, and atherosclerosis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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