Thermo Fisher Scientific CDw293 Polyclonal Antibody
BMPR1B 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 IHC(P/F)에서 사용 가능. Bovine, Human, Mouse, Rat 등 다양한 종에 반응. 항원 친화 크로마토그래피로 정제되었으며, PBS/glycerol 완충액에 보관. 연구용으로만 사용 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:10,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:100–1:1,000 |
| Immunohistochemistry (Frozen) (IHC-F) | 1:100–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Bovine, Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 238–502 of Human BMPR1B |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.0, with 20% glycerol |
| Contains | 0.025% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2545188 |
Product Specific Information
- Recommended positive controls: 293T, Neuro2A, C8D30, NIH-3T3, human BMPR1B-transfected 293T, Rat2
- Predicted reactivity: Mouse (98%), Rat (98%), Dog (98%), Pig (98%), Chicken (96%), Sheep (98%), Rhesus Monkey (99%), Bovine (99%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
BMPR1B (also known as ALK6, CDw293) is a transmembrane serine/threonine kinase and a member of the bone morphogenetic protein (BMP) receptor family, closely related to activin receptors ACVR1 and ACVR2.
It plays a key role in endochondral bone formation and embryogenesis.
BMPR1B is expressed in normal and cancerous prostate tissues and has relevance in endocrine therapy for prostate cancer.
BMPR1B receptor trafficking is also significant in FOP pathogenesis and human T-cell differentiation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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