Thermo Fisher Scientific KChIP2 Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:500–1:3,000

Product Specifications

Product Specific Information

• Keep as concentrated solution.
• Predicted reactivity: Mouse (98%), Rat (97%), Dog (99%), Chicken (95%), Rhesus Monkey (99%), Bovine (99%).
• Positive Control: 293T, A431, Raji, mouse brain.
• Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Target Information

Voltage-gated potassium (Kv) channels are key components of the potassium currents in the heart and central nervous system.
In the heart, Kv4 channels are involved in the repolarization phase of the action potential.
In the brain, these channels prevent reverse-propagation of action potentials.

KChIPs (Kv channel interacting proteins) are calcium-binding proteins associated with Kv4 channels that modulate their function.
There are three known KChIPs:

• KChIP1: Expressed in the brain
• KChIP2: Expressed in brain, heart, and lung (three isoforms: a, b, c)
• KChIP3: Also known as calsenilin and DREAM, expressed in brain and testis

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.