Thermo Fisher Scientific HDC Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human HDC. Recombinant protein control fragment (Product #RP-88649). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:HDC,uniProtId:P19113-1,ncbiNodeId:9606,antigenRange:82-199,antigenLength:662,antigenImageFileName:PA5-58580_HDC_P19113-1_Rabbit.svg,antigenImageFileNamePDP:PA5-58580_HDC_P19113-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.2 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2642339

Product Specific Information

Immunogen sequence: PALTSWPSLL GDMLADAINC LGFTWASSPA CTELEMNVMD WLAKMLGLPE HFLHHHPSSQ GGGVLQSTVS ESTLIALLAA RKNKILEMKT SEPDADESCL NARLVAYASD QAHSSVEK

Highest antigen sequence identity to the following orthologs: Mouse - 92%, Rat - 94%.

Target Information

The biogenic amine histamine is an important modulator of numerous physiologic processes, including neurotransmission, gastric acid secretion, and smooth muscle tone. The biosynthesis of histamine from histidine is catalyzed by the enzyme L-histidine decarboxylase (HDC; EC 4.1.1.22). This homodimeric enzyme is a pyridoxal phosphate (PLP)-dependent decarboxylase and is highly specific for its histidine substrate.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.